Disease: Acute Chest Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VWF P04275 von Willebrand factor Enzyme modulator 3.2E-25 0.408 0.885
VPS51 Q9UID3 VPS51 subunit of GARP complex 1.1E-08 0.452 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
THBD P07204 thrombomodulin 5.4E-02 0.457 0.769
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TFPI P10646 tissue factor pathway inhibitor Enzyme modulator 0.25 0.486 0.808
TCF21 O43680 transcription factor 21 0.83 0.537 0.692
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
ST2 suppression of tumorigenicity 2 0.576 0.692
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923
SELPLG Q14242 selectin P ligand 0.18 0.564 0.692
S100A9 P06702 S100 calcium binding protein A9 Calcium-binding protein 0.48 0.433 0.885
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PPARA Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 3.0E-02 0.432 0.885
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846